Our house is easily reachable from every part of Rome.
See the map
From Termini Railway Station:
Bus n. 64 or Underground Metro A to the Ottaviano-San Pietro Station.
From Fiumicino Airport:
Train FM 1 to Trastevere Station and connect there for St. Peter's Railway Station (departures every 15 minutes).
Other Buses:
Take Bus No. 64, 46, 982, 98, 881, 34, 115, or 116 (the last two depart from Terminal Gianicolo).